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OPPTS 885.4050: Microbial pesticide guidelines (avian oral, tier I)
OPPTS 885.4050: Microbial pesticide guidelines (avian oral, tier I)
The OPPTS 885.4050 Microbial Pesticide Test - Avian Oral, Tier I is an avian oral toxicity test conducted in accordance with EPA guidelines. Two bird species of differing diets (one insectivore and one herbivore, typically Bobwhite Quail) are administered a test substance orally over a period of 5 days and observed for 30 days or until all symptoms have subsided. Dosage amounts are calculated based on bird mass and chemical properties.
About our nonclinical animal research models: We provide the utmost care for our research animals and actively pursue advances in animal welfare. As well as ensuring the highest scientific, ethical and regulatory standards, selection of appropriate animal research models for development research is critical to developing safe and effective treatments, devices and products that protect and save lives. Just as we have ethical committee oversight for human trials, we have ethical committees overseeing all aspects of our global animal care and use programs. All of our core, nonclinical facilities are accredited by AAALAC. Learn more about our commitment to replacing, reusing and refining nonclinical research models.