Online Catalog
A collection of nonclinical studies & assays; customization is possible.

OECD 451/OCSPP 870.4200: Carcinogenicity studies

OECD 451/OCSPP 870.4200: Carcinogenicity studies

Carcinogenicity studies provide guidance on the 18-30 month observation of mice and rats for development of neoplastic lesions when exposed to various doses of test substance. 

Administration routes (oral, dermal or inhalation) depend on the toxicokinetic profile/physical characteristics of the test substance. 

Daily or weekly (more thorough) observation reports include animal weight, skin/fur evaluation and activity levels. 

Blood counts, necropsy and histopathology are also performed.


Mouse, Rat

Administration Routes

Dietary, Gavage

Industry Market

Chemical, Crop