There remains a significant unmet need in the treatment of rheumatoid arthritis (RA): there is no cure, treatments are often inconvenient and expensive, and safety is still a concern. We understand the challenges faced in RA clinical development and have the insight and experience to help you achieve success.
Understanding rheumatoid arthritis industry demands
- A trend towards more aggressive treatment under the 'treat to target' strategy
- Steady market growth due in part to aging population
- Movement towards early diagnosis and treatment of patients
- Expanded range of treatment options including novel biologics and small molecules
- Increasing availability of biosimilars making biologic treatments more accessible
- Biosimilars to infliximab, etanercept and adalimumab all approved
The nature of RA trials and the current development landscape cause a number of challenges in many RA clinical development programs. Labcorp has developed solutions to overcome each of these and help you along the path to success.
RA drug development pain points.
- Competitive biologics marketplace
- Difficulty in identifying investigators and locating patients
- Suboptimal patient retention over long trial periods
- Inefficient trial design, eligibility creep and inconsistencies in both subjective and objective trial outcomes
- Increasing demand for patients due to a small percentage participating in trials
- Inconsistencies in trial outcomes, which may be linked to inappropriate or incorrect use of PRO measures
- Inefficient patient recruitment, often a result of the competitive RA trial environment
- Delays if sites are unable to recruit the number of patients required in a timely manner
Extensive experience in rheumatoid arthritis clinical trials.
- Since 2012 we have managed 30 RA studies with 919 sites and 2,796 patients
- Proven experience in meeting RA trial timelines
- We have performance metrics on more than 1,400 rheumatologists
- We employ more than 1,200 RA-experienced staff, including more than 530 clinical research associates and nearly 150 project managers