Labcorp is a leading global life sciences company that includes contract research and developmental services to the pharmaceutical, medical technology, crop protection and chemical industries.
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Model Characterization and Tumor Immune Profile Assessment for Syngeneic RM-1 Murine Prostate Cancer in Male C57BL/6 Mice
AACR 2022 -- Syngeneic mouse tumor models are widely used to demonstrate activity of novel anti-cancer immunotherapies. RM-1 is a murine prostate cancer cell line derived from a Ras/Myc-induced prostate cancer that grows aggressively, is nonimmunogenic and androgen independent. Reproducible subcutaneous RM-1 tumor induction and growth parameters were determined in a pilot growth study (data not shown).