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Bring Forward the Best Candidate

Non-GLP Toxicology & Pharmacology

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Reduce timelines up to 40 days with our integrated lead optimization toxicology solution

Get the right study design working with a cross-functional team of experts

Anticipate and respond to challenges earlier — for better decision making

Improve Your Probability of Technical Success

You already know you need toxicology studies in your early development process. But how early? The earlier, the better. Experience half the molecule attrition in later phases by initiating non-GLP toxicology studies alongside your in vivo work. Our shorter pre- and post-study times reduce your schedule by as much as 40 days, helping you identify your best candidates, sooner.

Novel Compounds Require Novel Approaches

As you progress in your development journey, let us be your partner. We offer flexible design options, across multiple species, to help you determine which variables are the most crucial to isolate. By leveraging our integrated team of pharmacologists and pathologists, we help you find the right study solutions.

See the Unforeseen and Respond Accordingly

Early development is marked with unanticipated issues that can derail you in later phases. Through our integrated approach, we help you scientifically anticipate challenges and respond to them quickly. By integrating pharmacology, imaging and pathology into your toxicology study, you’re in a position to proactively resolve issues earlier in the journey — and more affordably.

Non-GLP Studies Toxicology Benefits

 


Make Better Decisions Earlier with an Integrated Team

Our cross-functional team of experts is prepared to anticipate and respond to challenges early so you can make well-informed decisions. 

Get Efficiently Executed non-GLP Toxicology Studies Across a Wide Range of Research Models:

  • Consultation on regulatory requirements and nonclinical studies
  • Evaluation of endocrine function
  • Evaluation of cardiovascular function in conscious/unrestrained animals
  • Lead optimization toxicology
    • Dose escalation and pilot studies in large animals
    • Dose range finding studies in large and small animals
    • Rodent screening and pilot studies
    • Toxicokinetic studies in large and small animals

Understand Your Compound’s Safety Profile With Pharmacology Studies:

  • Nonclinical, non-GLP, cardiovascular function characterization
  • Clinical convulsive risk nonclinical strategies
  • Endocrine function evaluation
  • Safety margin characterizations relative to therapeutic effects
  • Receptor occupancy assay to help guide decision making 
  • Regulatory consultation on nonclinical studies 

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